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L-Lysine-<sup>15</sup>N<sub>2</sub>

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Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0667S2

L-Asparagine-15N2 monohydrate (-)-Asparagine-<sup>15sup>N<sub>2sub> monohydrate; Asn-<sup>15sup>N<sub>2sub> monohydrate; Asparamide-<sup>15sup>N<sub>2sub> monohydrate	Endogenous Metabolite	Neurological Disease
L-Asparagine- ¹⁵N₂ (monohydrate) is the ¹⁵N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N1150S9

Thymidine-15N2 DThyd-<sup>15sup>N<sub>2sub>; NSC-<sup>15sup>N<sub>2sub>	DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus	Cancer
Thymidine- ¹⁵N₂ is the ¹⁵N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

HY-Y0271S

Urea-15N2 Carbamide-<sup>15sup>N<sub>2sub>; Carbonyldiamide-<sup>15sup>N<sub>2sub>	Endogenous Metabolite	Cardiovascular Disease Cancer
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-B2236S3

*DL-Lysine-15N2 hydrochloride* (±)-2,6-Diaminocaproic acid-<sup>15sup>N<sub>2sub> hydrochloride	Isotope-Labeled Compounds	Metabolic Disease
DL-Lysine- ¹⁵N₂ hydrochloride ((±)-2,6-Diaminocaproic acid- ¹⁵N₂ hydrochloride) is ¹⁵N labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.

HY-N0623S8

L-Tryptophan-15N2 Tryptophan-<sup>15sup>N<sub>2sub>; Tryptophane-<sup>15sup>N<sub>2sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-A0042S1

Rufinamide-15N,d2 CGP 33101-<sup>15sup>N,d<sub>2sub>; E 2080-<sup>15sup>N,d<sub>2sub>; RUF 331-<sup>15sup>N,d<sub>2sub>	Isotope-Labeled Compounds	Neurological Disease
Rufinamide- ¹⁵N,d₂ is the deuterium and ¹⁵N labeled Rufinamide[1]. Rufinamide is a new antiepileptic agent that differs structurally from other antiepileptic agents and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS)[2][3].

HY-B1028S

Pantethine-15N2 D-Pantethine-<sup>15sup>N<sub>2sub>; LBF disulfide-<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds	Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Pantethine- ¹⁵N₂ is the ¹⁵N₂ labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration ^[2] .

HY-B2236S2

*DL-Lysine-13C6,15N2 hydrochloride* (±)-2,6-Diaminocaproic acid-<sup>13sup>C<sub>6sub>,<sup>15sup>N<sub>2sub> hydrochloride	Isotope-Labeled Compounds	Metabolic Disease
DL-Lysine- ¹³C₆, ¹⁵N₂ hydrochloride ((±)-2,6-Diaminocaproic acid- ¹³C₆, ¹⁵N₂ hydrochloride) is ¹³C and ¹⁵N-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.

HY-17563S4

2'-Deoxyguanosine-15N5 Deoxyguanosine-<sup>15sup>N<sub>5sub>; Guanine deoxyriboside-<sup>15sup>N<sub>5sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine- ¹⁵N₅ (Deoxyguanosine- ¹⁵N₅; Guanine deoxyriboside- ¹⁵N₅) is ¹⁵N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-D0184S2

2'-Deoxycytidine-15N3 Deoxycytidine-<sup>15sup>N<sub>3sub>; Cytosine deoxyriboside-<sup>15sup>N<sub>3sub>; Deoxyribose cytidine-<sup>15sup>N<sub>3sub>	Endogenous Metabolite	Others
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-W011240S1

Hydroflumethiazide-15N2,13C,d2 Methforylthiazidine-<sup>15sup>N<sub>2sub>,<sup>13sup>C,d<sub>2sub>; Rontyl-<sup>15sup>N<sub>2sub>,<sup>13sup>C,d<sub>2sub>	Isotope-Labeled Compounds	Others
Hydroflumethiazide- ¹⁵N₂, ¹³C,d₂ is the ¹³C- and ¹⁵N-labeled Hydroflumethiazide[1].

HY-A0061S

Trifluridine-13C,15N2 Trifluorothymidine-<sup>13sup>C,<sup>15sup>N<sub>2sub>; 5-Trifluorothymidine-<sup>13sup>C,<sup>15sup>N<sub>2sub>; TFT-<sup>13sup>C,<sup>15sup>N<sub>2sub>	Thymidylate Synthase Nucleoside Antimetabolite/Analog HSV Orthopoxvirus	Cancer
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-N0623S6

L-Tryptophan-15N2,d8 Tryptophan-<sup>15sup>N<sub>2sub>,d<sub>8sub>; Tryptophane-<sup>15sup>N<sub>2sub>,d<sub>8sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-107372S4

Uridine triphosphate-15N2 dilithium UTP-<sup>15sup>N<sub>2sub> dilithium; Uridine 5'-triphosphate-<sup>15sup>N<sub>2sub> dilithium	Isotope-Labeled Compounds Endogenous Metabolite DNA/RNA Synthesis	Cardiovascular Disease Inflammation/Immunology Cancer
Uridine triphosphate- ¹⁵N₂ (UTP- ¹⁵N₂ dilithium; Uridine 5'-triphosphate- ¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-66005S4

Acetaminophen-13C2,15N Paracetamol-<sup>13sup>C<sub>2sub>,<sup>15sup>N; 4-Acetamidophenol-<sup>13sup>C<sub>2sub>,<sup>15sup>N; 4'-Hydroxyacetanilide-<sup>13sup>C<sub>2sub>,<sup>15sup>N	COX Bacterial Histone Acetyltransferase Parasite Endogenous Metabolite
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-Y1250S6

Fmoc-Gly-OH-13C2,15N Fmoc glycine-<sup>13sup>C<sub>2sub>,<sup>15sup>N; N-(9-Fluorenylmethoxycarbonyl)glycine-<sup>13sup>C<sub>2sub>,<sup>15sup>N; N-Fluorenylmethoxycarbonylglycine-<sup>13sup>C<sub>2sub>,<sup>15sup>N; NPC 14692-<sup>13sup>C<sub>2sub>-<sup>15sup>N; NSC 334288-<sup>13sup>C<sub>2sub>,<sup>15sup>N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-<sup>13sup>C<sub>2sub>,<sup>15sup>N	Isotope-Labeled Compounds Influenza Virus Bacterial	Infection
Fmoc-Gly-OH- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

HY-B1118S1

Secnidazole-13C2, 15N2 RP-14539-<sup>13sup>C<sub>2sub>, <sup>15sup>N<sub>2sub>; PM-185184-<sup>13sup>C<sub>2sub>, <sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds Parasite Antibiotic	Infection
Secnidazole- ¹³C₂, ¹⁵N₂ is the ¹³C₂, ¹⁵N₂ labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.

HY-138253S

2′,2′-Difluorodeoxyuridine-13C,15N2 dFdU-<sup>13sup>C,<sup>15sup>N<sub>2sub>; 2',2'-Difluoro-2'-deoxyuridine-<sup>13sup>C,<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds	Others
2′,2′-Difluorodeoxyuridine- ¹³C, ¹⁵N₂ (dFdU- ¹³C, ¹⁵N₂; 2',2'-Difluoro-2'-deoxyuridine- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled compound.

HY-100586

Ibuprofen L-lysine (±)-Ibuprofen L-Lysine
Ibuprofen ((±)-Ibuprofen) L-lysine is a potent orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen L-lysine inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen L-lysine is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen L-lysine can be used in the research of pain, swelling, inflammation, infection, immunology, cancers ^[2] .

HY-13417S

AICAR-13C2,15N Acadesine-<sup>13sup>C<sub>2sub>,<sup>15sup>N; AICA Riboside-<sup>13sup>C<sub>2sub>,<sup>15sup>N	Isotope-Labeled Compounds	Others
AICAR- ¹³C₂, ¹⁵N (Acadesine- ¹³C₂, ¹⁵N; AICA Riboside- ¹³C₂, ¹⁵N)is the ¹³C and ¹⁵N labeledAICAR(HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor ^[2] .

HY-D0844S

Glutathione oxidized-13C4,15N2 1 Publications Verification L-Glutathione oxidized-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>; GSSG-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>; Oxiglutatione-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

HY-N0545S

Taurocholic acid-13C2,15N sodium Sodium taurocholate-<sup>13sup>C<sub>2sub>,<sup>15sup>N; N-Choloyltaurine-<sup>13sup>C<sub>2sub>,<sup>15sup>N (sodium)	VEGFR Endogenous Metabolite	Inflammation/Immunology
Taurocholic acid- ¹³C₂, ¹⁵N (sodium) is the ¹³C- and ¹⁵N- labeled Taurocholic acid (sodium).

HY-13623S1

Entecavir-13C2,15N BMS200475-<sup>13sup>C<sub>2sub>,<sup>15sup>N; SQ34676-<sup>13sup>C<sub>2sub>,<sup>15sup>N	Isotope-Labeled Compounds	Infection
Entecavir- ¹³C₂, ¹⁵N (BMS200475- ¹³C₂, ¹⁵N; SQ34676- ¹³C₂, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC₅₀ of 3.75 nM in HepG2 cell.

HY-N0091S3

Hypoxanthine-13C2,15N Purin-6-ol-<sup>13sup>C<sub>2sub>,<sup>15sup>N; Sarcine-<sup>13sup>C<sub>2sub>,<sup>15sup>N	Endogenous Metabolite Isotope-Labeled Compounds	Others
Hypoxanthine- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled DL-Cystine[1].

HY-N0623S4

L-Tryptophan-13C11,15N2 Tryptophan-<sup>13sup>C<sub>11sub>,<sup>15sup>N<sub>2sub>; Tryptophane-<sup>13sup>C<sub>11sub>,<sup>15sup>N<sub>2sub>	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N1150S8

Thymidine-13C10,15N2 DThyd-<sup>13sup>C<sub>10sub>,<sup>15sup>N<sub>2sub>; NSC-<sup>13sup>C<sub>10sub>,<sup>15sup>N<sub>2sub>	DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus	Cancer
Thymidine- ¹³C₁₀, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

HY-13458S1

Droxidopa-13C2,15N hydrochloride L-DOPS-<sup>13sup>C<sub>2sub>,<sup>15sup>N hydrochloride; DOPS-<sup>13sup>C<sub>2sub>,<sup>15sup>N hydrochloride; SM5688-<sup>13sup>C<sub>2sub>,<sup>15sup>N hydrochloride	Adrenergic Receptor Isotope-Labeled Compounds	Neurological Disease
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].

HY-W014606

L-Lysine acetate	Endogenous Metabolite	Others Inflammation/Immunology
L-Lysine acetate is an essential amino acid. L-Lysine acetate can be research for vascular calcification (VC) and Acute pancreatitis ^[2].

HY-W015370

L-Lysine hydrate 3 Publications Verification	Endogenous Metabolite	Others Inflammation/Immunology
L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis ^[2].

HY-Y0219S

1,2,4-Triazole-13C2,15N3 s-Triazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>; Pyrrodiazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N0091S1

Hypoxanthine-13C,15N2 Purin-6-o-<sup>13sup>C,<sup>15sup>N<sub>2sub>; Sarcine-<sup>13sup>C,<sup>15sup>N<sub>2sub>	Bacterial	Infection
Hypoxanthine- ¹³C, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Furaltadone. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci

HY-16779B

*Fosravuconazole L-lysine* ethanolate** BMS-379224 L-Lysine ethanolate; E-1224 L-Lysine ethanolate	Fungal Parasite	Infection
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research ^[2] .

HY-13677S1

6-Mercaptopurine-13C2,15N Mercaptopurine-<sup>13sup>C<sub>2sub>,<sup>15sup>N; 6-MP-<sup>13sup>C<sub>2sub>,<sup>15sup>N	Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite	Cancer
6-Mercaptopurine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

HY-B1449S

Uridine-15N2

β-Uridine <sup>15sup>N<sub>2sub>
Nucleoside Antimetabolite/Analog Endogenous Metabolite Cancer

Uridine- ¹⁵N₂ is the ¹⁵N labeled Uridine[1].

Uridine-15N2 β-Uridine <sup>15sup>N<sub>2sub>	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Cancer
Uridine- ¹⁵N₂ is the ¹⁵N labeled Uridine[1].

HY-B0456S

Riboflavin-13C4,15N2 Vitamin B2-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>; E101-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Riboflavin- ¹³C₄, ¹⁵N₂is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-N0091S4

Hypoxanthine-13C2,15N-1 Purin-6-ol-<sup>13sup>C<sub>2sub>,<sup>15sup>N-1; Sarcine-<sup>13sup>C<sub>2sub>,<sup>15sup>N-1	Endogenous Metabolite Isotope-Labeled Compounds	Others
Hypoxanthine- ¹³C₂, ¹⁵N-1 is a ¹⁵N-labeled and ¹³C-labled 4-Hydroxyestrone[1].

HY-15252

*Reparixin L-lysine* salt** 45+ Cited Publications Repertaxin L-Lysine salt	CXCR	Inflammation/Immunology Endocrinology Cancer
Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation.

HY-150712S

Uridine triphosphate-13C9,15N2 dilithium UTP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>2sub> dilithium; Uridine 5'-triphosphate-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>2sub> dilithium	Isotope-Labeled Compounds	Others
Uridine triphosphate- ¹³C₉, ¹⁵N₅ dilithium is the ¹³C and ¹⁵N labeled Uridine triphosphate dilithium .

HY-D0184S3

2'-Deoxycytidine-13C9,15N3 Deoxycytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Cytosine deoxyriboside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Deoxyribose cytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-107372S

Uridine triphosphate-13C9,15N2 sodium UTP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>2sub> sodium; Uridine 5'-triphosphate-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>2sub> sodium	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Infection Cancer
Uridine triphosphate- ¹³C₉, ¹⁵N₂ (sodium) is a labeled Uridine triphosphate sodium. Uridine triphosphate sodium can be used in nucleic acid synthesis.

HY-N0455AS

L-Arginine-15N2 hydrochloride (S)-(+)-Arginine-<sup>15sup>N<sub>2sub> hydrochloride	NO Synthase Endogenous Metabolite	Others
L-Arginine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-17563S1

2'-Deoxyguanosine-13C10,15N5 Deoxyguanosine-<sup>13sup>C<sub>10sub>,<sup>15sup>N<sub>5sub>; Guanine deoxyriboside-<sup>13sup>C<sub>10sub>,<sup>15sup>N<sub>5sub>	Isotope-Labeled Compounds	Cancer
2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (Deoxyguanosine- ¹³C₁₀, ¹⁵N₅; Guanine deoxyriboside- ¹³C₁₀, ¹⁵N₅) is a ¹³C- and ¹⁵N-labeled 2'-Deoxyguanosine (HY-17563).

HY-149157

L-Lysine orotate

Others Metabolic Disease

L-Lysine orotate is a salt of L-lysine and orotic acid that can potentiate the toxicity of an extract of the mushroom Amanita phalloides .

L-Lysine orotate	Others	Metabolic Disease
L-Lysine orotate is a salt of L-lysine and orotic acid that can potentiate the toxicity of an extract of the mushroom Amanita phalloides .

HY-B0456S1

Riboflavin-5-Phosphate-13C4,15N2-1 Vitamin B2-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>-1; E101-<sup>13sup>C<sub>4sub>,<sup>15sup>N<sub>2sub>-1	Isotope-Labeled Compounds Endogenous Metabolite	Others
Riboflavin-5-Phosphate- ¹³C₄, ¹⁵N₂-1 is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-W392933S

Thymidine 5'-monophosphate-15N2 Thymidine-5'-phosphate-<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds	Others
Thymidine 5'-monophosphate- ¹⁵N₂ is the ¹⁵N labeled Thymidine 5'-monophosphate[1].

HY-B0508S1

Ornidazole-13C2,15N2 Ro 7-0207-<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds Bacterial Parasite Antibiotic	Infection
Ornidazole- ¹³C₂, ¹⁵N₂ is the ¹³C, ¹⁵N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.

HY-N0157S1

Orotic acid-13C,15N2 monohydrate 6-Carboxyuracil-<sup>13sup>C,<sup>15sup>N<sub>2sub> monohydrate; Vitamin B13-<sup>13sup>C,<sup>15sup>N<sub>2sub> monohydrate	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Metabolic Disease
Orotic acid- ¹³C, ¹⁵N₂ (monohydrate) is the ¹³C and ¹⁵N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].

HY-B0503S

2-Thiouracil-13C,15N2 Thiouracil-<sup>13sup>C,<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds NO Synthase	Endocrinology Cancer
2-Thiouracil- ¹³C, ¹⁵N₂ is the ¹³C, ¹⁵N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.

HY-N0097S3

Guanosine-15N5 DL-Guanosine-<sup>15sup>N<sub>5sub>; Vernine-<sup>15sup>N<sub>5sub>	HSV Endogenous Metabolite	Infection
Guanosine- ¹⁵N₅ is the ¹⁵N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].

HY-B0250S1

Lamivudine-13C,15N2,d2 BCH-189-<sup>13sup>C,<sup>15sup>N<sub>2sub>,d<sub>2sub>	Isotope-Labeled Compounds HBV Reverse Transcriptase HIV	Infection
Lamivudine-13C,15N2,d2 (BCH-189-13C,15N2,d2) is a 13C, 15N, and deuterium labeled Lamivudine (HY-B0250). Lamivudine is an orally active and blood-brain barrier permeable nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine inhibits HIV reverse transcriptase 1 and 2 and hepatitis B virus (HBV) reverse transcriptase ^[2] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015370

L-Lysine hydrate 3 Publications Verification	Structural Classification Classification of Application Fields Source classification Amino acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis ^[2].

HY-N0470

L-Lysine hydrochloride 3 Publications Verification	Cardiovascular Disease Structural Classification Microorganisms Animals Classification of Application Fields Source classification Amino acids Inflammation/Immunology Disease Research Fields Endocrinology	Virus Protease Endogenous Metabolite
L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.

HY-N0469

*L-Lysine* 3 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Virus Protease
L-lysine is an essential amino acid ^[2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions ^[2].

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[2] .

HY-W014606

L-Lysine acetate	Structural Classification Classification of Application Fields Source classification Amino acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
L-Lysine acetate is an essential amino acid. L-Lysine acetate can be research for vascular calcification (VC) and Acute pancreatitis ^[2].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[2] .

HY-N1324

Sanggenon N	Structural Classification Flavanonols Flavonoids Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N7404

Nε,Nε,Nε-Trimethyllysine chloride Ne-(Trimethyl)-L-Lysine chloride; H-Lys(Me)3-OH chloride	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[2] .

HY-W048838

Acetyl-L-lysine	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Acetyl-L-lysine is an endogenous metabolite.

HY-113426

Nepsilon-Acetyl-L-lysine	Structural Classification Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine is a derivative of the amino acid lysine.

HY-135072

N,N',N''-Triacetylchitotriose	Infection Polysaccharides Microorganisms Classification of Application Fields Animals Source classification Disease Research Fields Saccharides	Others
N,N',N''-Triacetylchitotriose is a competitive inhibitor of lysozyme .

HY-N12267

N,N′-Diferuloylputrescine	Structural Classification Zea mays L. Gramineae Source classification Phenols Polyphenols Plants	Melanocortin Receptor
N,N′-Diferuloylputrescine is a inhibitor of pigmentation with 57% reduction. N,N′-Diferuloylputrescine significantly reduces the protein level of MITF. N,N′-Diferuloylputrescine has strong antioxidant activities as radical scavengers against reactive oxygen species .

HY-113374A

N1,N12-Diacetylspermine dihydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.

HY-130778

N,N'-Diacetylchitobiose	Structural Classification Microorganisms Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields Saccharides	Endogenous Metabolite
N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli .

HY-129912

N1,N8-Diacetylspermidine	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N1,N8-Diacetylspermidine is a polyamines in the human urine . N1,N8-Diacetylspermidine is useful as prognostic indicators after treatment and during follow-up examination of cancer patients ^[2].

HY-129912A

N1,N8-Diacetylspermidine hydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N1,N8-Diacetylspermidine hydrochloride is a polyamines in the human urine . N1,N8-Diacetylspermidine hydrochloride is useful as prognostic indicators after treatment and during follow-up examination of cancer patients ^[2].

HY-113137

N2,N2-Dimethylguanosine 3 Publications Verification	Structural Classification Natural Products Classification of Application Fields Other disease Source classification Disease markers Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-W049735

N,N,O-Tridesmethylvenlafaxine	Monophenols Classification of Application Fields Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N,N,O-Tridesmethylvenlafaxine is an endogenous metabolite.

HY-B0504S

Creatinine-d3 NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetylserine (N-Acetyl-L-serine) can bind to CysB apoprotein. N-acetylserine is the physiological inducer of cysteine biosynthesis. N-Acetylserine can stimulate in vitro cysJIH transcription ^[2].

HY-N12302

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine	Structural Classification Source classification Phenols Polyphenols Lycium ruthenicum Murray Plants Solanaceae	Others
N1-Dihydrocaffeoyl, N10-caffeoyl spermidine is a natural product that can be isolated from Lycium ruthenicum Murr. .

HY-111054A

N-methyl-N-dithiocarboxyglucamine sodium MDCG sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound ¹⁰⁹Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity .

HY-N4188

N-Benzyloctadecanamide N-Benzylstearamide	Alkaloids Classification of Application Fields Source classification Plants Brassicaceae Disease Research Fields Endocrinology Lepidium meyenii Walp.	Others
N-Benzyloctadecanamide (N-Benzylstearamide) is a macamide, a distinct class of secondary metabolites in Lepidium meyenii Walp. (Maca) .

HY-N3218

N1,N10-Bis(p-coumaroyl)spermidine	Structural Classification Source classification Phenols Polyphenols Plants Papaveraceae	Others
N1,N10-Bis(p-coumaroyl)spermidine is a phenylpropanoid that can be isolated from Fagales pollen .

HY-W027951

N,N'-Dimethylthiourea DMTU	Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Allium sativum Linn. Plants Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action ^[2].

HY-113056A

N1-Acetylspermidine hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA ^[2] .

HY-W040795

N2-Acetylguanine	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an K_d value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent .

HY-112175

N-Acetylhistamine 2 Publications Verification N-Omega-acetylhistamine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Histamine Receptor Endogenous Metabolite
N-Acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.

HY-N0086

N6-Methyladenosine 5 Publications Verification 6-Methyladenosine; N-Methyladenosine	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Influenza Virus Endogenous Metabolite
N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

HY-Y1055

Guanine 3 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .

HY-N2410

N-trans-Feruloyltyramine N-feruloyltyramine; Moupinamide	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Phenols Polyphenols Piperaceae Plants Inflammation/Immunology Disease Research Fields Piper nigrum Linn.	Reactive Oxygen Species Apoptosis
N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H₂O₂-induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research ^[2].

HY-W007426

N-Methylbenzylamine	Alkaloids Classification of Application Fields Source classification Other Diseases Ephedraceae Plants Disease Research Fields Ephedra sinica Stapf	Others
N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products .

HY-32135

N-Phenethylbenzamide	Natural Products Magnoliaceae Liriodendron tulipifera L. Plants	Others
N-Phenethylbenzamide is an active compound. N-Phenethylbenzamide can be extracted from Liriodendron tulipifera. N-Phenethylbenzamide can be used for the research of inflammatory diseases .

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-116832

Retrorsine N-oxide	Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Plants Compositae Baptisia australis (L.) R. Br. Disease Research Fields Cancer	Others
Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides ^[2].

HY-126854

N-Acetyllactosamine N-Acetyl-D-lactosamine	Structural Classification Natural Products Microorganisms	Endogenous Metabolite
N-Acetyllactosamine (LacNAc), a nitrogen-containing disaccharide, is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects ^[2].

HY-N9897

N-Benzylheptadecanamide	Structural Classification Natural Products Source classification Plants Brassicaceae Lepidium meyenii Walp.	Biochemical Assay Reagents
N-Benzylheptadecanamide is an N-benzylamide that can be obtained from Lepidium meyenii .

HY-N10533

N-Benzylpentadecanamide	Structural Classification Natural Products Plants Brassicaceae Lepidium meyenii Walp.	Others
N-Benzylpentadecanamide is a natural N-benzylamide found in Maca (Lepidium meyenii) .

HY-Y0068

N-Acetyl-L-phenylalanine 1 Publications Verification N-Acetylphenylalanine	Microorganisms Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetyl-L-phenylalanine (N-Acetylphenylalanine), the principal acylamino acid in Escherichia coli, is synthesized from L-phenylalanine and acetyl-CoA .

HY-121975

N-Cyclohexanecarbonylpentadecylamine	Structural Classification Natural Products Source classification Endogenous metabolite	Others
N-Cyclohexanecarbonylpentadecylamine (Compound 1) is an inhibitor of N-Acylethanolamine hydrolyzing acid amidase (NAAA) with an IC₅₀ of 4.5 μM. N-Cyclohexanecarbonylpentadecylamine can be used in the research of inflammation and pain .

HY-113253A

N8-Acetylspermidine dihydrochloride	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N8-Acetylspermidine dihydrochloride is a polyamine.

HY-W019670

N4-Acetylcytidine	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N4-Acetylcytidine is an endogenous metabolite.

HY-N12252

N-Acetylcytisine	Structural Classification Alkaloids Leguminosae Other Alkaloids Source classification Plants Genista maderensis (Webb & Berthel.) Lowe	Others
N-Acetylcytisine is a kind of alkaloid. N-Acetylcytisine can be isolated from T. maderensis .

HY-126487

H-Arg-Lys-OH	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-Arg-Lys-OH is a dipeptide formed from L-arginyl and L-lysine residues .

Cat. No.	Product Name	Chemical Structure

HY-N0667S2

L-Asparagine-15N2 monohydrate
L-Asparagine- ¹⁵N₂ (monohydrate) is the ¹⁵N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N1150S9

Thymidine-15N2
Thymidine- ¹⁵N₂ is the ¹⁵N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

HY-Y0271S

Urea-15N2
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-B2236S3

*DL-Lysine-15N2 hydrochloride*
DL-Lysine- ¹⁵N₂ hydrochloride ((±)-2,6-Diaminocaproic acid- ¹⁵N₂ hydrochloride) is ¹⁵N labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.

HY-N0623S8

L-Tryptophan-15N2
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-A0042S1

Rufinamide-15N,d2
Rufinamide- ¹⁵N,d₂ is the deuterium and ¹⁵N labeled Rufinamide[1]. Rufinamide is a new antiepileptic agent that differs structurally from other antiepileptic agents and is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS)[2][3].

HY-B1028S

Pantethine-15N2

Pantethine- ¹⁵N₂ is the ¹⁵N₂ labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration ^[2] .

HY-B2236S2

*DL-Lysine-13C6,15N2 hydrochloride*
DL-Lysine- ¹³C₆, ¹⁵N₂ hydrochloride ((±)-2,6-Diaminocaproic acid- ¹³C₆, ¹⁵N₂ hydrochloride) is ¹³C and ¹⁵N-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.

HY-17563S4

2'-Deoxyguanosine-15N5
2'-Deoxyguanosine- ¹⁵N₅ (Deoxyguanosine- ¹⁵N₅; Guanine deoxyriboside- ¹⁵N₅) is ¹⁵N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.

HY-D0184S2

2'-Deoxycytidine-15N3
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-W011240S1

Hydroflumethiazide-15N2,13C,d2

Hydroflumethiazide- ¹⁵N₂, ¹³C,d₂ is the ¹³C- and ¹⁵N-labeled Hydroflumethiazide[1].

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-N0623S6

L-Tryptophan-15N2,d8
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-107372S4

Uridine triphosphate-15N2 dilithium

Uridine triphosphate- ¹⁵N₂ (UTP- ¹⁵N₂ dilithium; Uridine 5'-triphosphate- ¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-66005S4

Acetaminophen-13C2,15N
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-Y1250S6

Fmoc-Gly-OH-13C2,15N
Fmoc-Gly-OH- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

HY-B1118S1

Secnidazole-13C2, 15N2
Secnidazole- ¹³C₂, ¹⁵N₂ is the ¹³C₂, ¹⁵N₂ labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.

HY-138253S

2′,2′-Difluorodeoxyuridine-13C,15N2

2′,2′-Difluorodeoxyuridine- ¹³C, ¹⁵N₂ (dFdU- ¹³C, ¹⁵N₂; 2',2'-Difluoro-2'-deoxyuridine- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled compound.

HY-13417S

AICAR-13C2,15N
AICAR- ¹³C₂, ¹⁵N (Acadesine- ¹³C₂, ¹⁵N; AICA Riboside- ¹³C₂, ¹⁵N)is the ¹³C and ¹⁵N labeledAICAR(HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor ^[2] .

HY-D0844S

Glutathione oxidized-13C4,15N2 1 Publications Verification
Glutathione oxidized- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

HY-N0545S

Taurocholic acid-13C2,15N sodium

Taurocholic acid- ¹³C₂, ¹⁵N (sodium) is the ¹³C- and ¹⁵N- labeled Taurocholic acid (sodium).

HY-13623S1

Entecavir-13C2,15N
Entecavir- ¹³C₂, ¹⁵N (BMS200475- ¹³C₂, ¹⁵N; SQ34676- ¹³C₂, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC₅₀ of 3.75 nM in HepG2 cell.

HY-N0091S3

Hypoxanthine-13C2,15N

Hypoxanthine- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled DL-Cystine[1].

HY-N0623S4

L-Tryptophan-13C11,15N2
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N1150S8

Thymidine-13C10,15N2
Thymidine- ¹³C₁₀, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

HY-13458S1

Droxidopa-13C2,15N hydrochloride
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].

HY-Y0219S

1,2,4-Triazole-13C2,15N3

NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N0091S1

Hypoxanthine-13C,15N2
Hypoxanthine- ¹³C, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Furaltadone. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci

HY-13677S1

6-Mercaptopurine-13C2,15N
6-Mercaptopurine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

HY-B1449S

Uridine-15N2

Uridine- ¹⁵N₂ is the ¹⁵N labeled Uridine[1].

HY-B0456S

Riboflavin-13C4,15N2
Riboflavin- ¹³C₄, ¹⁵N₂is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-N0091S4

Hypoxanthine-13C2,15N-1

Hypoxanthine- ¹³C₂, ¹⁵N-1 is a ¹⁵N-labeled and ¹³C-labled 4-Hydroxyestrone[1].
HY-150712S

Uridine triphosphate-13C9,15N2 dilithium

Uridine triphosphate- ¹³C₉, ¹⁵N₅ dilithium is the ¹³C and ¹⁵N labeled Uridine triphosphate dilithium .

HY-D0184S3

2'-Deoxycytidine-13C9,15N3
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-107372S

Uridine triphosphate-13C9,15N2 sodium
Uridine triphosphate- ¹³C₉, ¹⁵N₂ (sodium) is a labeled Uridine triphosphate sodium. Uridine triphosphate sodium can be used in nucleic acid synthesis.

HY-N0455AS

L-Arginine-15N2 hydrochloride
L-Arginine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-17563S1

2'-Deoxyguanosine-13C10,15N5

2'-Deoxyguanosine- ¹³C₁₀, ¹⁵N₅ (Deoxyguanosine- ¹³C₁₀, ¹⁵N₅; Guanine deoxyriboside- ¹³C₁₀, ¹⁵N₅) is a ¹³C- and ¹⁵N-labeled 2'-Deoxyguanosine (HY-17563).

HY-B0456S1

Riboflavin-5-Phosphate-13C4,15N2-1
Riboflavin-5-Phosphate- ¹³C₄, ¹⁵N₂-1 is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

HY-W392933S

Thymidine 5'-monophosphate-15N2

Thymidine 5'-monophosphate- ¹⁵N₂ is the ¹⁵N labeled Thymidine 5'-monophosphate[1].

HY-B0508S1

Ornidazole-13C2,15N2
Ornidazole- ¹³C₂, ¹⁵N₂ is the ¹³C, ¹⁵N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.

HY-N0157S1

Orotic acid-13C,15N2 monohydrate

Orotic acid- ¹³C, ¹⁵N₂ (monohydrate) is the ¹³C and ¹⁵N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].

HY-B0503S

2-Thiouracil-13C,15N2
2-Thiouracil- ¹³C, ¹⁵N₂ is the ¹³C, ¹⁵N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.

HY-N0097S3

Guanosine-15N5
Guanosine- ¹⁵N₅ is the ¹⁵N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].

HY-B0250S1

Lamivudine-13C,15N2,d2
Lamivudine-13C,15N2,d2 (BCH-189-13C,15N2,d2) is a 13C, 15N, and deuterium labeled Lamivudine (HY-B0250). Lamivudine is an orally active and blood-brain barrier permeable nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine inhibits HIV reverse transcriptase 1 and 2 and hepatitis B virus (HBV) reverse transcriptase ^[2] .

HY-W727879

Upadacitinib-15N,d2

Upadacitinib- ¹⁵N,d₂ (ABT-494- ¹⁵N,d₂) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- ¹⁵N,d₂ (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC₅₀=43 nM). Upadacitinib- ¹⁵N,d₂ (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- ¹⁵N,d₂ (ABT-494) can be used for several autoimmune disorders research ^[2].

HY-17427S

Emtricitabine-15N,d2
Emtricitabine- ¹⁵N,d₂ is a ¹⁵N-labeled and deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.

HY-108213S1

Inosinic acid-15N4 dilithium
Inosinic acid- ¹⁵N₄ dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is ¹⁵N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite ^[2].

HY-N0091S7

Hypoxanthine-15N4 1 Publications Verification
Hypoxanthine- ¹⁵N₄ is the ¹⁵N labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].

HY-16973S

Fluralaner-13C2,15N,d3
Fluralaner- ¹³C₂, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.

HY-D0187S

L-Glutathione reduced-13C2,15N
L-Glutathione reduced- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

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Species:	Human (277) Porcine (1) Rhesus Macaque (2) Rat (6) Bovine (2) E.coli (4) Cynomolgus (6) Rabbit (1) Canine (2) Pig (1) Virus (561) Mouse (43) Staphylococcus aureus (1)
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Source:	HEK293 (531) E. coli Cell-free (9) CHO (2) Sf9 insect cells (185) P. pastoris (21) E. coli (174)


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L-Lysine-<sup>15</sup>N<sub>2</sub>

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